Nicktoons Racing 2 is a sequel to 2000's Nicktoons Racing.
While all of the characters return from the previous game, new ones arrive.
- Jimmy Neutron- A boy who has big brown hair and saves the day with his inventions. Drives a UFO.
- Sheen- A boy who is a big fan of Ultralord. Drives a Zeenu racer.
- Dudley Puppy- A T.U.F.F. agent who chews his butt. Drives a car that resembles his green bone.
- Kitty Katswell- Dudley's partner, and also a Teenage cat. Drives the T.U.F.F. Moblie.
- Skipper- The leader of the Penguins of Madagascar. Drives a Hot Rod.
- Squidward- A squid who gets annoyed by Spongebob & Patrick. Drives a car shaped like his clarinet.
- Chuckie- A baby who has orange hair & sometimes he worries alot. Drives a car shaped like his teddy.
- Oblina- A monster who was a cameo in the intro of Nicktoons Racing 1. Drives a big car with tennis balls on each side.
- Timmy- A fariygod son who has Cosmo, Wanda, & Poof at his side. Drives the Pink Car seen in the intro of The Fairly OddParents.
- Mr. Krabs- A red crab who is a cheapstake. Drives a Ketchup-Shaped car.
- Zim- A irken who wants to rule the earth. Drives the VOOT rider.
- Gir- A robot who dress up like a puppy. Drives a turtle-shaped car.
- Po- A overweight panda who teams up with the Furious 5. Drives a china speeder.
- King Julien- A lemur who annoys the Penguins Of Madagascar. Drives a golf cart.
- Danny Phantom- A ghost boy who is good freinds with Sam & Tucker. Drives the ghost car.
- Jenny- A robot girl who was bulit by her mother. Drives a pink go-kart with boxing gloves.
- Otis- A cow who lives on a farm & acts like a human. Drives a Tractor.
- Aang- an airbender who must save the day. Drives the Tornado Racer from Sonic & SEGA: All-Stars Racing.
- Tak- A pupununu boy who has a juju wand. Drives the JuJu Speeder.
- Bev Bighead- A green toad with orange hair, blue pants, and a pink shirt. Drives a purple monster truck.
- El Tigre- An amazing superhero from Miracle City! Drives the B Dasher from Mario Kart DS.
- Ricky Sprocket- The world's most famous showbiz boy. Drives a HUGE limo.
- Victor Volt & Anita Knight- A duo of UZZ agents going on a mission. Together, they drive the Red Fire from Mario Kart: Double Dash!!.
- Blue- A blue puppy who plays with Steve and Joe. Drives a baby stroller.
- Dora- A cute little explorer who is best friends with Boots. Drives a rainbow-colored rocket.
- Diego- A hero who goes on adventures with Alicia and Baby Jaguar. Drives a buffalo-shaped tank.
- Wubbzy- A little boy who loves Kickety-Kick Ball and makes friends with Walden and Widget. Drives the Sprinter from Mario Kart Wii.
- Kai-Lan- A Chinese-American kid who is good friends with Tolee, Rintoo, Hoho, Lulu, and Ye Ye. Drives the Birthday Girl from Mario Kart 7.
- Krusty Krab Prix (Spongebob Squarepants): Mr. Krabs has been protecting the secert formula for a couple weeks, so he makes a Speedway based on his restraunt.
- Cynthia Speedway (Rugrats): You'll race through Cynthia's Mansion, Malibu Beach, & Hollywood. Everything Cynthia owns is found here.
- Gritty City Circuit (Hey Arnold!): Gritty City Circuit is now back and better than ever before!
- Monster Mania (Ahh!!! Real Monsters): Think this was scary in Nicktoons Racing 1? Well now, it's Halloween this time!
- T.U.F.F. HQ (T.U.F.F. Puppy): The HeadQuarters from T.U.F.F. Puppy is now a race track! So be on the look out for a rare T.U.F.F. Blaster powerup.
- Highway Attack (Ren & Stimpy): Race on a big highway to win the race!
- Retroland (Jimmy Neutron): Retroland has lots of boost areas to drive in, so be on the lookout for a grim reaper.
- Sporcket Rig (Ricky Sprocket): Race on a highway, but watch out for those curves because you will fall.
- Zim's School (invader Zim): Race around Zim's Classroom, Study Hall, & The Lunchroom.
- Central Park Zoo (The Penguins of Madagascar): Central Park Zoo is totally crowded with lots of people!
- Jellyfish Felids (Spongebob Squarepants): Race around Spongebob's favorite place with Jellyfish fans!
- Hong Kong Harbor (Ren & Stimpy): Stimpy Statues are everywhere here!
- Inside Statue of Liberty (Penguins of Madagascar): Race your way to the top of the Statue's head and New York of course!
- Flying Dutchman's Stadium (Spongebob Squarepants): Ghost Pirates will attack with weapons so you can scare them on this track.
- Dora's Exploring Speedway (Dora the Explorer): Are you ready to race and explore in this awesome race course?!
- Kai-Lan's Space Rainbow (Ni Hao, Kai-Lan): The ladybugs are rooting for you!